{"id":119,"date":"2024-04-11T14:36:55","date_gmt":"2024-04-11T12:36:55","guid":{"rendered":"https:\/\/odelialaboratoires.fr\/?page_id=119"},"modified":"2024-04-12T10:47:09","modified_gmt":"2024-04-12T08:47:09","slug":"ressources-etudes","status":"publish","type":"page","link":"https:\/\/odelialaboratoires.fr\/index.php\/ressources-etudes\/","title":{"rendered":"Ressources &amp; \u00c9tudes"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"119\" class=\"elementor elementor-119\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f5bb846 e-flex e-con-boxed e-con e-parent\" data-id=\"4f5bb846\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d3bdd70 elementor-widget elementor-widget-heading\" data-id=\"5d3bdd70\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h3 class=\"elementor-heading-title elementor-size-default\">Ressources scientifiques<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a2207f8 elementor-widget elementor-widget-text-editor\" data-id=\"7a2207f8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><b>Akram Khan M., Afzal M. Chemical composition of Nigella sativa Linn: Part 2 Recent advances.<\/b><\/p><p><b>Inflammopharmacology, 2016, 24(2-3):67-79. doi: 10.1007\/s10787-016-0262-7.<\/b><\/p><p><b>Ali B.H., Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother. Res., 2003, 17,<\/b><\/p><p><b>299-305.<\/b><\/p><p><b>Alkhatib H. et al. Thymoquinone content in marketed black seed oil in Malaysia. J Pharm Bioallied Sci. 2020,<\/b><\/p><p><b>12(3): 284\u2013288. doi: 10.4103\/jpbs.JPBS_208_20<\/b><\/p><p><b>Alshwyeh H.A., Aldosary S.K., Ilowefah M.A., Shahzad R., Shehzad A., Bilal S., Lee I.-J., Mater J.A.A., Al-Shakhoari<\/b><\/p><p><b>F.N., Alqahtani W.A., Kamal N., Mediani A. Biological Potentials and Phytochemical Constituents of Raw and<\/b><\/p><p><b>Roasted Nigella arvensis and Nigella sativa. Molecules 2022, 27, 550.<\/b><\/p><p><b>https:\/\/doi.org\/10.3390\/molecules27020550<\/b><\/p><p><b>Alzohairy MA, Khan AA, Alsahli MA, Almatroodi SA, Rahmani AH. Protective Effects of Thymoquinone, an Active<\/b><\/p><p><b>Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative<\/b><\/p><p><b>Stress and Inflammation. Molecules. 2021; 26(11):3218. https:\/\/doi.org\/10.3390\/molecules26113218<\/b><\/p><p><b>Amin B., Hosseinzadeh H. Black Cumin (Nigella sativa) and Its Active Constituent, Thymoquinone: An Overview<\/b><\/p><p><b>on the Analgesic and Anti-inflammatory Effects. Planta Med. 2016, 82(1-2):8-16. doi: 10.1055\/s-0035-1557838.<\/b><\/p><p><b>Ansary J, Giampieri F, Forbes-Hernandez TY, Regolo L, Quinzi D, Gracia Villar S, Garcia Villena E, Tutusaus Pifarre<\/b><\/p><p><b>K, Alvarez-Suarez JM, Battino M, Cianciosi D. Nutritional Value and Preventive Role of Nigella sativa L. and Its<\/b><\/p><p><b>Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical Studies.<\/b><\/p><p><b>Molecules. 2021; 26(8): 2108. https:\/\/doi.org\/10.3390\/molecules26082108<\/b><\/p><p><b>Anses, 2018. Avis de l\u2019Anses : \u00c9tat des lieux des alternatives aux antibiotiques en vue de diminuer leur usage en<\/b><\/p><p><b>\u00e9levage : \u00c9laboration d\u2019une m\u00e9thode d\u2019\u00e9valuation des publications scientifiques et r\u00e9sultats. Rapport<\/b><\/p><p><b>d\u2019expertise collective, f\u00e9vrier 2018, Saisine n\u00b0 2013-SA-0122.<\/b><\/p><p><b>Anses, 2021. Note d\u2019appui scientifique et technique de l\u2019Agence nationale de s\u00e9curit\u00e9 sanitaire de<\/b><\/p><p><b>l\u2019alimentation, de l\u2019environnement et du travail relative aux plantes et huiles essentielles les plus impliqu\u00e9es<\/b><\/p><p><b>dans les d\u00e9clarations de nutrivigilance signal\u00e9es \u00e0 l\u2019Anses, 17 d\u00e9cembre 2021. Appui scientifique et technique<\/b><\/p><p><b>de l\u2019Anses, Demande n\u00b0 \u00ab 2021-AST-0133 \u00bb<\/b><\/p><p><b>Anses, 2021. Phytoth\u00e9rapie et aromath\u00e9rapie chez les animaux producteurs de denr\u00e9es alimentaires.<\/b><\/p><p><b>Proposition d\u2019une m\u00e9thodologie d\u2019\u00e9valuation du risque pour le consommateur, Rapport d\u2019expertise collective,<\/b><\/p><p><b>D\u00e9cembre 2021, Saisine n\u00b0 2020-SA-0083, https:\/\/www.anses.fr\/fr\/system\/files\/ERCA2020SA0083Ra.pdf<\/b><\/p><p><b>ANSM, 2021 : Liste A des plantes m\u00e9dicinales utilis\u00e9es traditionnellement (16\/01\/2021) ; Liste B des plantes<\/b><\/p><p><b>m\u00e9dicinales utilis\u00e9es traditionnellement en l\u2019\u00e9tat ou sous forme de pr\u00e9paration dont les effets ind\u00e9sirables<\/b><\/p><p><b>potentiels sont sup\u00e9rieurs au b\u00e9n\u00e9fice th\u00e9rapeutique attendu (16\/01\/2021)<\/b><\/p><p><b>https:\/\/ansm.sante.fr\/pharmacopee\/liste-des-plantes-medicinales-utilisees-traditionnellement#L<\/b><\/p><p><b>Aronson JK (Ed). Meyler&#8217;s Side Effects of Herbal Medicines, 2e ed., 2009, Elsevier ed.<\/b><\/p><p><b>Arr\u00eat\u00e9 du 4 octobre 2019 portant radiation de m\u00e9dicaments hom\u00e9opathiques de la liste des sp\u00e9cialit\u00e9s<\/b><\/p><p><b>pharmaceutiques remboursables aux assur\u00e9s sociaux mentionn\u00e9e au premier alin\u00e9a de l\u2019article L. 162-17 du<\/b><\/p><p><b>code de la s\u00e9curit\u00e9 sociale, Journal Officiel de la R\u00e9publique Fran\u00e7aise du 8 octobre 2019.<\/b><\/p><p><b>ARRETE ROYAL du 29 AOUT 1997 relatif \u00e0 la fabrication et au commerce de denr\u00e9es alimentaires compos\u00e9es ou<\/b><\/p><p><b>contenant des plantes ou pr\u00e9parations de plantes (Moniteur Belge 21.XI.1997), version consolid\u00e9e 2017 par<\/b><\/p><p><b>A.R. du 24 janvier 2017 (Moniteur Belge 10.II.2017).<\/b><\/p><p><b>Ayurvedic Pharmacopoeia of India \u2013 Plants Monographs (vol. 1) : disponible \u00e0 :<\/b><\/p><p><b>http:\/\/www.ayurveda.hu\/api\/API-Vol-1.pdf<\/b><\/p><p><b>Barnes et al. (Ed), 2007. Herbal medicines. 2e \u00e9d. Pharmaceutical Press ; Barnes J., Anderson L.A., Phillipson J.D.<\/b><\/p><p><b> Herbal medicines. 3e \u00e9d. Pharmaceutical Press.<\/b><\/p><p><b>46<\/b><\/p><p><b>Botnick I, Xue W, Bar E, Ibdah M, Schwartz A, Joel DM, Lev E, Fait A, Lewinsohn E. Distribution of primary and<\/b><\/p><p><b>specialized metabolites in Nigella sativa seeds, a spice with vast traditional and historical uses. Molecules. 2012<\/b><\/p><p><b>; 17(9): 10159-77. doi: 10.3390\/molecules170910159.<\/b><\/p><p><b>Bruneton J. 2016. Pharmacognosie, phytochimie, plantes m\u00e9dicinales. 5e \u00e9dition, \u00c9ditions Tec et Doc, Lavoisier.<\/b><\/p><p><b>Bruneton J., 2002. Phytoth\u00e9rapie : les donn\u00e9es de l\u2019\u00e9valuation. \u00c9ditions Tec et Doc, Lavoisier.<\/b><\/p><p><b>Burdock G.A. Assessment of black cumin (Nigella sativa L.) as a food ingredient and putative therapeutic agent.<\/b><\/p><p><b>Regul Toxicol Pharmacol. 2022, 128:105088. doi: 10.1016\/j.yrtph.2021.105088.<\/b><\/p><p><b>Butt MS, Imran M, Imran A, Arshad MS, Saeed F, Gondal TA, Shariati MA, Gilani SA, Tufail T, Ahmad I, Rind NA,<\/b><\/p><p><b>Mahomoodally MF, Islam S, Mehmood Z. Therapeutic perspective of thymoquinone: A mechanistic treatise.<\/b><\/p><p><b>Food Sci Nutr. 2021; 9(3): 1792-1809. doi: 10.1002\/fsn3.2070.<\/b><\/p><p><b>Capasso F., Gaginella T. S., Grandolini G., Izzo A.A., 2003. Phytotherapy &#8211; A quick reference to herbal medicine.<\/b><\/p><p><b>Springer.<\/b><\/p><p><b>Cheikh-Rouhou S., Besbes S., Hentati B., Blecker C., Deroanne C., Attia H. Nigella sativa L. Chemical composition<\/b><\/p><p><b>and phytochemical characteristics of lipid fraction. Food Chem., 2007, 101, 673-681.<\/b><\/p><p><b>Commission Europ\u00e9enne. Register of Feed Additives pursuant to Regulation (EC) N\u00b0 1831\/2003. Version 2020.<\/b><\/p><p><b>ISBN 978-92-79-67663-5, doi: 10.2875\/48257<\/b><\/p><p><b>Commission Europ\u00e9enne. R\u00c8GLEMENT (CE) No 1334\/2008 DU PARLEMENT EUROP\u00c9EN ET DU CONSEIL du 16<\/b><\/p><p><b>d\u00e9cembre 2008 relatif aux ar\u00f4mes et \u00e0 certains ingr\u00e9dients alimentaires poss\u00e9dant des propri\u00e9t\u00e9s<\/b><\/p><p><b>aromatisantes qui sont destin\u00e9s \u00e0 \u00eatre utilis\u00e9s dans et sur les denr\u00e9es alimentaires et modifiant le r\u00e8glement<\/b><\/p><p><b>(CEE) no 1601\/91 du Conseil, les r\u00e8glements (CE) no 2232\/96 et (CE) no 110\/2008 et la directive 2000\/13\/CE,<\/b><\/p><p><b>Journal Officiel de l\u2019Union Europ\u00e9enne, 31.12.2008.<\/b><\/p><p><b>Dalli M, Bekkouch O, Azizi S-e, Azghar A, Gseyra N, Kim B. Nigella sativa L. Phytochemistry and Pharmacological<\/b><\/p><p><b>Activities: A Review (2019\u20132021). Biomolecules. 2022; 12(1):20. https:\/\/doi.org\/10.3390\/biom12010020<\/b><\/p><p><b>DGCCRF, 2016. Liste des plantes \u00e9ligibles \u00e0 l&#8217;article 15.<\/b><\/p><p><b>https:\/\/www.economie.gouv.fr\/files\/files\/directions_services\/dgccrf\/securite\/teleicare\/Table-Plantes.pdf<\/b><\/p><p><b>DGCCRF, 2019 : Liste des plantes dont sont extraites des huiles essentielles dont l\u2019usage en alimentation<\/b><\/p><p><b>humaine est consid\u00e9r\u00e9 comme \u00e9tant traditionnel, au sens de l\u2019article 7 du d\u00e9cret n\u00b02006-352 relatif aux<\/b><\/p><p><b>compl\u00e9ments alimentaires et Liste des huiles essentielles dont l\u2019emploi ne peut \u00eatre admis.<\/b><\/p><p><b>https:\/\/www.economie.gouv.fr\/dgccrf\/complements-alimentaires-plantes<\/b><\/p><p><b>Dobetsberger C., Buchbauer G. Actions of essential oils on the central nervous system: An updated review.<\/b><\/p><p><b>Flavour Fragr. J. 2011, 26, 300\u2013316. DOI 10.1002\/ffj.2045<\/b><\/p><p><b>EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Younes M, Aggett P, Aguilar F,<\/b><\/p><p><b>Crebelli R, Dusemund B, Filipi\u010d M, Frutos MJ, Galtier P, Gott D, Gundert-Remy U, Lambr\u00e9 C, Leblanc JC,<\/b><\/p><p><b>Lillegaard IT, Moldeus P, Mortensen A, Oskarsson A, Stankovic I, Waalkens-Berendsen I, Woutersen RA,<\/b><\/p><p><b>Andrade RJ, Fortes C, Mosesso P, Restani P, Arcella D, Pizzo F, Smeraldi C, Wright M. Scientific opinion on the<\/b><\/p><p><b>safety of green tea catechins. EFSA J. 2018; 16(4): e05239. doi: 10.2903\/j.efsa.2018.5239.<\/b><\/p><p><b>Essid R., Rahali F. Z., Msaada K., Sghair I., Hammami M., Bouratbine A., Aoun K., Limam F. Ind. Crops. Prod.<\/b><\/p><p><b>2015, 77, 795-802.<\/b><\/p><p><b>European Food Safety Authority; Compendium of botanicals reported to contain naturally occurring substances<\/b><\/p><p><b>of possible concern for human health when used in food and food supplements. EFSA Journal 2012;10(5):2663.<\/b><\/p><p><b>[60 pp.] doi:10.2903\/j.efsa.2012.2663.<\/b><\/p><p><b>European Food Safety Authority; Compendium of botanicals that have been reported to contain toxic,<\/b><\/p><p><b>addictive, psychotropic or other substances of concern on request of EFSA. EFSA Journal 2009; 7(9):281. [100<\/b><\/p><p><b>pp.]. doi:10.2903\/j.efsa.2009.281.<\/b><\/p><p><b>Evans W., 2009. Trease and Evans\u2019 pharmacognosy, 16th ed. Saunders.<\/b><\/p><p><b>Farag MA, Gad HA, Heiss AG, Wessjohann LA. Metabolomics driven analysis of six Nigella species seeds via<\/b><\/p><p><b>UPLC-qTOF-MS and GC-MS coupled to chemometrics. Food Chem. 2014 ; 151: 333-42. doi:<\/b><\/p><p><b>10.1016\/j.foodchem.2013.11.032.<\/b><\/p><p><b>47<\/b><\/p><p><b>FDA, CFR &#8211; Code of Federal Regulations Title 21 (version en vigueur le 1er octobre 2021) : Code of Federal<\/b><\/p><p><b>Regulations] [Title 21, Volume 3] [CITE: 21CFR182.10] SUBCHAPTER B &#8211; FOOD FOR HUMAN CONSUMPTION;<\/b><\/p><p><b>PART 182 &#8212; SUBSTANCES GENERALLY RECOGNIZED AS SAFE, Subpart A &#8211; General Provisions, Sec. 182.10 Spices<\/b><\/p><p><b>and other natural seasonings and flavorings : \u201cCaraway, black (black cumin), Nigella sativa L.\u201d<\/b><\/p><p><b>Franchomme P., Jollois R., P\u00e9no\u00ebl D. L&#8217;aromath\u00e9rapie exactement. Editions R. JOLLOIS, 2003 (EAN :<\/b><\/p><p><b>9782878190014).<\/b><\/p><p><b>Gardner Z, McGuffin M. Botanical Safety Handbook, 2nd Edition, 2013, AHPA ed.<\/b><\/p><p><b>Ghanya N. Al-Naqeep, Maznah M. Ismail, Adel S. Al-Zubairi and Norhaizan M. Esa. Nutrients Composition and<\/b><\/p><p><b>Minerals Content of Three Different Samples of Nigella sativa L. Cultivated in Yemen. Asian Journal of Biological<\/b><\/p><p><b>Sciences, 2009, 2: 43-48.<\/b><\/p><p><b>Gharby S., et al. Chemical investigation of Nigella sativa L. seed oil produced in Morocco. Journal of the Saudi<\/b><\/p><p><b>Society of Agricultural Sciences, 2015, 14(2), 172-177, https:\/\/doi.org\/10.1016\/j.jssas.2013.12.001<\/b><\/p><p><b>Hadi V, Pahlavani N, Malekahmadi M, Nattagh-Eshtivani E, Navashenaq JG, Hadi S, et al. Nigella sativa in<\/b><\/p><p><b>controlling Type 2 diabetes, cardiovascular, and rheumatoid arthritis diseases: Molecular aspects. J Res Med Sci<\/b><\/p><p><b>2021; 26: 20.<\/b><\/p><p><b>Hadi V. et al. Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status<\/b><\/p><p><b>in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. Avicenna J.<\/b><\/p><p><b>Phytomed. 2016;6(1):34-43.<\/b><\/p><p><b>Han A., Shi D. The efficacy of Nigella sativa supplementation for asthma control: a meta-analysis of randomized<\/b><\/p><p><b>controlled studies. Adv Dermatol Allergol 2021; XXXVIII (4): 561\u2013565. doi:<\/b><\/p><p><b>https:\/\/doi.org\/10.5114\/ada.2020.93220<\/b><\/p><p><b>Hannan MA, Rahman MA, Sohag AAM, Uddin MJ, Dash R, Sikder MH, Rahman MS, Timalsina B, Munni YA,<\/b><\/p><p><b>Sarker PP, Alam M, Mohibbullah M, Haque MN, Jahan I, Hossain MT, Afrin T, Rahman MM, Tahjib-Ul-Arif M,<\/b><\/p><p><b>Mitra S, Oktaviani DF, Khan MK, Choi HJ, Moon IS, Kim B. Black Cumin (Nigella sativa L.): A Comprehensive<\/b><\/p><p><b>Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety. Nutrients. 2021; 13(6):1784.<\/b><\/p><p><b>https:\/\/doi.org\/10.3390\/nu13061784<\/b><\/p><p><b>Hannan MA, Zahan MS, Sarker PP, Moni A, Ha H, Uddin MJ. Protective Effects of Black Cumin (Nigella sativa)<\/b><\/p><p><b>and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights.<\/b><\/p><p><b>International Journal of Molecular Sciences. 2021; 22(16): 9078. https:\/\/doi.org\/10.3390\/ijms22169078<\/b><\/p><p><b>Heinrich M., Barnes J., Gibbons S., Williamson E.M., 2012. Fundamentals of pharmacognosy and phytotherapy.<\/b><\/p><p><b>Elsevier.<\/b><\/p><p><b>Hossain MS, Sharfaraz A, Dutta A, Ahsan A, Masud MA, Ahmed IA, Goh BH, Urbi Z, Sarker MMR, Ming LC. A<\/b><\/p><p><b>review of ethnobotany, phytochemistry, antimicrobial pharmacology and toxicology of Nigella sativa L. Biomed<\/b><\/p><p><b>Pharmacother. 2021; 143:112182. doi: 10.1016\/j.biopha.2021.112182.<\/b><\/p><p><b>Hwang, Cartron, Khachemoune. A review of Nigella sativa plant-based therapy in dermatology. International<\/b><\/p><p><b>Journal of Dermatology 2021, 60, e493\u2013e499. doi: 10.1111\/ijd.15615<\/b><\/p><p><b>Kabir Y, Akasaka-Hashimoto Y, Kubota K, Komai M. Volatile compounds of black cumin (Nigella sativa L.) seeds<\/b><\/p><p><b>cultivated in Bangladesh and India. Heliyon. 2020, 6(10):e05343. doi: 10.1016\/j.heliyon.2020.e05343.<\/b><\/p><p><b>Khabbazi A, Javadivala Z, Seyedsadjadi N, Malek Mahdavi A. A Systematic Review of the Potential Effects of<\/b><\/p><p><b>Nigella sativa on Rheumatoid Arthritis. Planta Med. 2020; 86(7): 457-469. doi: 10.1055\/a-1143-8521.<\/b><\/p><p><b>Khare C.P. Ayurvedic Pharmacopoeial plant drugs \u2013 expanded therapeutics, CRC Press, 2016, ISBN 978-1-4665-<\/b><\/p><p><b>9000-7 (e-book)<\/b><\/p><p><b>Kheirouri S, Hadi V, Alizadeh M. Immunomodulatory Effect of Nigella sativa Oil on T Lymphocytes in Patients<\/b><\/p><p><b>with Rheumatoid Arthritis. Immunol Invest. 2016, 45(4):271-83. doi: 10.3109\/08820139.2016.1153649.<\/b><\/p><p><b>Khonche A, Huseini HF, Gholamian M, Mohtashami R, Nabati F, Kianbakht S. Standardized Nigella sativa seed<\/b><\/p><p><b>oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease: a<\/b><\/p><p><b>randomized, double-blind and placebo-controlled clinical trial. J Ethnopharmacol. 2019;234:106\u201311.<\/b><\/p><p><b>48<\/b><\/p><p><b>Koshak A. et al. Medicinal benefits of Nigella sativa in bronchial asthma: A literature review. Saudi Pharm J.<\/b><\/p><p><b>2017, 25(8):1130-1136. doi: 10.1016\/j.jsps.2017.07.002.<\/b><\/p><p><b>Leong X.-F. et al. Anti-Inflammatory Effects of Thymoquinone in Atherosclerosis: A Mini Review. Front<\/b><\/p><p><b>Pharmacol. 2021; 12: 758929. doi: 10.3389\/fphar.2021.758929<\/b><\/p><p><b>Mahboubi M, Mohammad Taghizadeh Kashani L, Mahboubi M. Nigella sativa fixed oil as alternative treatment<\/b><\/p><p><b>in management of pain in arthritis rheumatoid. Phytomedicine. 2018; 46: 69-77. doi:<\/b><\/p><p><b>10.1016\/j.phymed.2018.04.018.<\/b><\/p><p><b>Mahdavi R. et al. Nigella sativa oil with a calorie-restricted diet can improve biomarkers of systemic<\/b><\/p><p><b>inflammation in obese women: A randomized double-blind, placebo-controlled clinical trial. J Clin Lipidol 2016,<\/b><\/p><p><b>10(5):1203-11. doi: 10.1016\/j.jacl.2015.11.019.<\/b><\/p><p><b>Mahmoudvand H., Tavakoli R., Sharififar F., Minaie K., Ezatpour B., Jahanbakhsh S., Sharifi I. Pharm. Biol. 2015,<\/b><\/p><p><b>53, 1052-1057.<\/b><\/p><p><b>Majdalawieh A.F., Fayyad M.W. Immunomodulatory and anti-inflammatory action of Nigella sativa and<\/b><\/p><p><b>thymoquinone: A comprehensive review. International Immunopharmacology 2015, 28, 295\u2013304. doi:<\/b><\/p><p><b>10.1016\/j.intimp.2015.06.023.<\/b><\/p><p><b>Majdalawieh AF, Yousef SM, Abu-Yousef IA. Thymoquinone, a major constituent in Nigella sativa seeds, is a<\/b><\/p><p><b>potential preventive and treatment option for atherosclerosis. Eur J Pharmacol. 2021; 909: 174420. doi:<\/b><\/p><p><b>10.1016\/j.ejphar.2021.174420.<\/b><\/p><p><b>Malekian S, Ghassab-Abdollahi N, Mirghafourvand M, Farshbaf-Khalili A. The effect of Nigella sativa on<\/b><\/p><p><b>oxidative stress and inflammatory biomarkers: a systematic review and meta-analysis. J Complement Integr<\/b><\/p><p><b>Med. 2021 ;18(2):235-259. doi: 10.1515\/jcim-2019-0198.<\/b><\/p><p><b>Malik S, Singh A, Negi P, Kapoor VK. Thymoquinone: A small molecule from nature with high therapeutic<\/b><\/p><p><b>potential. Drug Discov Today. 2021; 26(11): 2716-2725. doi: 10.1016\/j.drudis.2021.07.013.<\/b><\/p><p><b>Marsik P. et al. In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1-<\/b><\/p><p><b>and -2-catalyzed prostaglandin E2 biosyntheses. Planta Med. 2005, 71(8):739-42. doi: 10.1055\/s-2005-871288.<\/b><\/p><p><b>Melo F. H., Ven\u00e2ncio E. T., de Sousa D. P., Fran\u00e7a Fonteles M. M., de Vasconcelos S. M., Viana G. S., de Sousa F.<\/b><\/p><p><b> Fundam. Clin. Pharmacol. 2009. 24(4), 437<\/b><\/p><p><b>Ministero della Salute. Allegato 1 al DM 10 agosto 2018 sulla disciplina dell&#8217;impiego negli integratori alimentari<\/b><\/p><p><b>di Sostanze e preparati vegetali come aggiornato con Decreto 9 gennaio 2018 e da ultimo con Decreto 26 luglio<\/b><\/p><p><b>2019.<\/b><\/p><p><b>Mohammed N.K. et al. The Effects of Different Extraction Methods on Antioxidant Properties, Chemical<\/b><\/p><p><b>Composition, and Thermal Behavior of Black Seed (Nigella sativa L.) Oil. Evidence-Based Complementary and<\/b><\/p><p><b>Alternative Medicine, 2016, article ID 6273817; https:\/\/doi.org\/10.1155\/2016\/6273817<\/b><\/p><p><b>Montazeri RS, Fatahi S, Sohouli MH, Abu-Zaid A, Santos HO, G\u0103man MA, Shidfar F. The effect of Nigella sativa<\/b><\/p><p><b>on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized<\/b><\/p><p><b>controlled trials. J Food Biochem. 2021;45(4):e13625. doi: 10.1111\/jfbc.13625.<\/b><\/p><p><b>Nawarathne et al. Development of Novel Topical Cosmeceutical Formulations from Nigella sativa L. with<\/b><\/p><p><b>Antimicrobial Activity against Acne-Causing Microorganisms. The Scientific World Journal, 2019, article ID<\/b><\/p><p><b>5985207, doi: 10.1155\/2019\/5985207.<\/b><\/p><p><b>Paris R.R., Moyse H. Mati\u00e8re m\u00e9dicale (3 tomes). 3<\/b><\/p><p><b>e \u00e9d, 1971. Masson Ed.<\/b><\/p><p><b>Pelkonen, O., Duez, P., Vuorela, P.M., Vuorela, H. (Eds.). Toxicology of Herbal Products. 2017, Springer ed.<\/b><\/p><p><b>Perveen T., Haider S., Kanwal S., Haleem D. J., Pakistan J. Pharm. Sci. 2009, 22, 139.<\/b><\/p><p><b>Raza, M.; Alghasham, A.A.; Alorainy, M.S.; El-Hadiyah, T.M. Potentiation of Valproate-induced Anticonvulsant<\/b><\/p><p><b>Response by Nigella sativa Seed Constituents: The Role of GABA Receptors. Int. J. Health Sci. 2008, 2, 15\u201325.<\/b><\/p><p><b>Rouhou S. Cheikh, Besbes S., Hentati B., Blecker C., Deroanne C., Attia H. Nigella sativa L. Chemical composition<\/b><\/p><p><b>and phytochemical characteristics of lipid fraction. Food Chem., 2007, 101, 673-681.<\/b><\/p><p><b>49<\/b><\/p><p><b>Sahebkar A, Beccuti G, Simental-Mend\u00eda LE, Nobili V, Bo S. Nigella sativa (black seed) effects on plasma lipid<\/b><\/p><p><b>concentrations in humans: A systematic review and meta-analysis of randomized placebo-controlled trials.<\/b><\/p><p><b>Pharmacol Res. 2016; 106: 37-50. doi: 10.1016\/j.phrs.2016.02.008.<\/b><\/p><p><b>Saima A., Showkat R., Kanchan K., Babar A., Mohad A. A study of the chemical composition of black cumin oil<\/b><\/p><p><b>and its effect on penetratin enhancement from transdermal formulation. Nat. Prod.Res. 2010, 24(12), 1151\u2013<\/b><\/p><p><b>1157.<\/b><\/p><p><b>Salehi B, Quispe C, Imran M, Ul-Haq I, \u017divkovi\u0107 J, Abu-Reidah IM, Sen S, Taheri Y, Acharya K, Azadi H, Del Mar<\/b><\/p><p><b>Contreras M, Segura-Carretero A, Mnayer D, Sethi G, Martorell M, Abdull Razis AF, Sunusi U, Kamal RM, Rasul<\/b><\/p><p><b>Suleria HA, Sharifi-Rad J. Nigella Plants &#8211; Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical<\/b><\/p><p><b>Studies. Front Pharmacol. 2021; 12:625386. doi: 10.3389\/fphar.2021.625386.<\/b><\/p><p><b>Sarkar C, Jamaddar S, Islam T, Mondal M, Islam MT, Mubarak MS. Therapeutic perspectives of the black cumin<\/b><\/p><p><b>component thymoquinone: A review. Food Funct. 2021 ; 12(14): 6167-6213. doi: 10.1039\/d1fo00401h.<\/b><\/p><p><b>Singh S, Das SS, Singh G, Schuff C, de Lampasona MP, Catal\u00e1n CA. Composition, in vitro antioxidant and<\/b><\/p><p><b>antimicrobial activities of essential oil and oleoresins obtained from black cumin seeds (Nigella sativa L.).<\/b><\/p><p><b>Biomed Res Int. 2014; 2014: 918209. doi: 10.1155\/2014\/918209.<\/b><\/p><p><b>Soleymani S. et al. The effect of a hydrogel made by Nigella sativa L. on acne vulgaris: A randomized double-<\/b><\/p><p><b>blind clinical trial. Phytother. Res. 2020, 34(11):3052-3062. doi: 10.1002\/ptr.6739.<\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c78f90e elementor-align-center elementor-mobile-align-center elementor-widget elementor-widget-button\" data-id=\"3c78f90e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/odelialaboratoires.fr\/index.php\/nigella-sativa\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">D\u00e9couvrir la Nigelle<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-43de9b7b e-con-full e-flex e-con e-parent\" data-id=\"43de9b7b\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t<div class=\"elementor-element elementor-element-70a8a77e elementor-widget elementor-widget-heading\" data-id=\"70a8a77e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">\u00a9 Tous droits r\u00e9serv\u00e9s<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Ressources scientifiques Akram Khan M., Afzal M. Chemical composition of Nigella sativa Linn: Part 2 Recent advances. Inflammopharmacology, 2016, 24(2-3):67-79. doi: 10.1007\/s10787-016-0262-7. Ali B.H., Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother. Res., 2003, 17, 299-305. Alkhatib H. et al. Thymoquinone content in marketed black seed oil in Malaysia. J Pharm Bioallied Sci. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-119","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/pages\/119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/comments?post=119"}],"version-history":[{"count":13,"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/pages\/119\/revisions"}],"predecessor-version":[{"id":358,"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/pages\/119\/revisions\/358"}],"wp:attachment":[{"href":"https:\/\/odelialaboratoires.fr\/index.php\/wp-json\/wp\/v2\/media?parent=119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}